DMT, or N, N-Dimethyltryptamine, is a chemical molecule naturally present in plants and animals. It is among other things the active hallucinogenic compound of psilohuasca and ayahuasca. The best known use of DMT is with the famous ayahuasca which is the Quechua name of a tea from the shrub Psychotria viridis, which is used for ritual purposes by the indigenous peoples of Amazonia.
DMT can also be smoked with a pipe like with Bufo Alvarius or Changa or blown in the nose like with Yopo. Taken in these ways, it produces a powerful but short-lived hallucinogenic state of 5 to 30 min but is considered one of the most intense psychedelic experiences there is.
It can also retain its psychoactive properties in other forms, in particular psilocybin (4-PO-DMT, present in psilocybe mushrooms used in particular for psilohuasca).